Ben Clarke
Position: Visiting PhD student

Project: Stress responses in ALS


Life in the Lab

I am interested in astrocytes – cells that surround neurons, providing them with support and protecting them from damage. For reasons we dont fully understand, astrocytes in ALS patients are unable to support motor neurons and actually release chemicals that contribute towards motor neuron death.

I make astrocytes from ALS patients skin cells that have been turned into induced pluripotent stem cells (iPSCs). I then stress out these cells a dish and compare the astrocytes made from ALS patients with those from healthy people. From these experiments we hope to find the molecular abnormalities that occur in ALS patient astrocytes, so that in future drugs can be designed to fix them.

Life outside the Lab

I am a keen runner and enjoy travelling, music and the theatre.

Related links

LinkedIn | Twitter

Rickie Patani

Lab Supervisor

Yiran Wang

Postdoctoral researcher

Jasmine Harley

PhD student

Helen Devine

PhD Student

Oliver Ziff

PhD student

Camilla Højland Knudsen

PhD student

Ben Clarke

Visiting PhD student

Viren Pandya

PhD student

Doaa Taha

PhD student

Jacob Neeves

PhD student