Helen Devine
Position: Phd Student

Project: Why do motor neurons die in Kennedy’s Disease?

 

Life in the Lab

Kennedy’s Disease also known as Spinal and Bulbar Muscular Atrophy (SBMA) is a rare motor neuron disease and there is no cure. This leads to weakness in patients’ arms, legs and face muscles. Most research in SBMA has been undertaken in cell and animal models of SBMA. These studies have revealed several possible pathways that may be involved in motor neuron degeneration but it is not clear how relevant these results are to the human disease. I will use motor neurons grown from induced pluripotent stem cells (iPSCs) which have been made from patients skin cells to try and find out how and why motor nerves die in this disease. I will then try and treat the cells to see if I can stop them dying.

Life outside the Lab

I love playing and watching sport, especially tennis.




Helen Devine

Phd Student

Rubika Balendra

Phd Student

Daniel Coftas

Phd Student

Claire Hall

Phd Student

Martina Halleger

Postdoc

Jasmine Harley

Research technician

Luke Hill

Phd Student

Philip Smethurst

Postdoc

Rickie Patani

Lab Supervisor

Fredrique Rau

Postdoc