Sarah Wiethoff
Position: Alumni

Project: Can stem cells be used to study diseases of the cerebellum?


Life in the Lab

The cerebellum is the part of the brain which controls motor coordination and balance As a doctor I am particularly interested in inherited conditions where nerve cells in the cerebellum die.
In my research I am trying to assess whether human induced pluripotent stem cells can be used to study these diseases. I am particularly studying whether the iPSCs can grow into cerebellar cells and then I will use them to try and understand whether they can be used to study different cerebellar diseases called the spinocerebellar ataxias (SCAs) and to identify possible drug targets. My work is funded by the Brain Research Trust.

Life outside the Lab

In my freetime, I like to relax. I do that best when being surrounded by water or moving (or ideally a combination of both). I love exploring nature, foreign countries and cultures and being curious about life.

Rickie Patani

Lab Supervisor

Yiran Wang

Postdoctoral researcher

Jasmine Harley

PhD student

Helen Devine

PhD Student

Oliver Ziff

PhD student

Camilla Højland Knudsen

PhD student

Ben Clarke

Visiting PhD student

Viren Pandya

PhD student

Doaa Taha

PhD student

Jacob Neeves

PhD student