Fredrique Rau
Position: Alumni

Project: Hereditary Spastic Paraplegia: Why cells die and how we can treat them.


Life in the Lab

Recent discoveries in MND implicate problems with RNA (the genetic code for proteins) as a common feature in motor neuron death. In particular, mutations lead to modification resulting in the accumulation of TDP-43 protein. Gene expression regulation is a very sophisticated process involving several steps and TDP-43 is involved in this process.
My research project aims to understand how the accumulation of TDP-43 affects gene expression and how this contributes to motor neuron disease.


Life outside the Lab

During my free time I like to practice sports (swimming and horse riding), but also going to music concerts, theatre and ballet. I like traveling to explore different countries, cultures and food.


Rickie Patani

Lab Supervisor

Yiran Wang

Postdoctoral researcher

Jasmine Harley

PhD student

Helen Devine

PhD Student

Oliver Ziff

PhD student

Camilla Højland Knudsen

PhD student

Ben Clarke

Visiting PhD student

Viren Pandya

PhD student

Doaa Taha

PhD student

Jacob Neeves

PhD student