Project: Is MND a prion disease?
Life in the Lab
I am a post doc in the lab and the focus of my research is on ‘TDP-43’ which is the most common abnormal protein found in the brains and spinal cord of patients with motor neuron disease. One idea is that this protein folds into an abnormal shape which adversely affects the motor neurons and cause them to die. It is thought that the protein acts in a similar way to a virus or bacteria, where it can replicate and spread throughout the brain causing the death of neurons. This is also how cells die in another type of brain disease called ‘prion disease’ an example you may have heard of is CJD. I am currently investigating whether or not the TDP-43 protein could work in a similar way by studying it in motor neuron cells in a dish.
Life outside the Lab
During my free time I like to compose and play contemporary/classical piano music. I also like to attend live music events and concerts. I also enjoy reading popular science literature, drawing, travelling and socialising with friends.
Camilla Højland Knudsen
Visiting PhD student